"Lambert-Eaton myasthenic syndrome (LEMS) is an autoimmune disease — a disease in which the immune system attacks the body's own tissues. The attack occurs at the connection between nerve and muscle (the neuromuscular junction) and interferes with the ability of nerve cells to send signals to muscle cells." "Initially, LEMS can cause weakness in the upper legs and hips, leading to difficulty walking, and weakness in the upper arms and shoulders, which can make self-care difficult. Like myasthenia gravis (MG), it also can result in weakness of the eye muscles and those involved in talking, swallowing and chewing, but these symptoms are usually mild."

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